Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p202 | (1) | WCRB2014

Different roads to fertility: distinct molecular and physiological strategies warrant the phenotype ‘high fertility’ in two outbred mouse models

Weitzel Joachim , Sobczak Alexander , Michaelis Marten

Animal models are valuable tools in fertility research. Worldwide >800 transgenic or knockout mouse models are available showing a reproductive phenotype; almost all of them exhibit an infertile or at least subfertile phenotype. In contrast, animal models revealing an improved fertility phenotype are barely described. Here, we present data on two outbred mouse models showing a ‘high fertility’ phenotype. These mouse lines have been generated via selection over a ...